Administration of Tirunelveli district in Tamil Nadu is having the District Collector as the head with his office at the district collectorate. Some of the responsibilities of the District Collector include maintenance of law & order, coordinating a number of welfare and development activities in the district, etc. The Collector is assisted by the District Revenue Officer in matters of land revenue, land matters, public distribution system, etc. and by the Project Officer, District Rural Development Agency for a list of development schemes. There are a number of other officers who help the Collector of the district in his work of general administration.

Some of the officers who assist the Collector in his general administration are Personal Assistant (General), Additional Personal Assistant (Land), Personal Assistant (Development), Personal Assistant (Agriculture), Personal Assistant (Noon Meal Program), Personal Assistant (Small Savings), Personal Assistant (Survey and Land Records), Personal Assistant (Accounts), Special Deputy Collector (PGRC), Assistant Director (Audit), Assistant Director (Panchayats), Assistant Director (Mines), Special Deputy Collector (Stamps), District Adi-Dravidar and Tribal Welfare Officer, Assistant Director (Town Panchayats), District Backward class welfare Officer, District Supply Officer, Assistant Commissioner (Excise), Public Relations Officer and Inspection Cell Officer. There is one municipal corporation, seven municipalities, thirty eight town panchayats, four hundred and twenty five village panchayats, five hundred and fifty nine villages and sixty firkas in the Tirunelveli district of Tamil Nadu state.

At the divisional level, the Sub Collectors or Revenue Divisional Officers help the Collector in the functioning of the administration. In the district of Tirunelveli there are three Revenue Divisions which are Tirunelveli, Tenkasi and Cheranmahadevi. Tahsildars are the officers` in-charge at the taluk level. In this district, there are eleven taluks which include Tirunelveli, Alangulam, Sankarankovil, Palayamkottai, Ambasamudram, Tenkasi, Nanguneri, Radhapuram, Veerakeralampudur, Shenkottai and Sivagiri.

The Panchayat Union Commissioners at block level in the district of Tirunelveli in the Tamil Nadu state are the officers` in-charge for implementing all the developmental works recommended by the Government at the Block level. There are nineteen Panchayat Unions (Blocks) in this district which are Palayamkottai, Manur, Melaneelithanallur, Sankarankovil, Ambasamudram, Kuruvikulam, Cheranmahadevi, Kalakadu, Nanguneri, Pappakudi, Kadayam, Alangulam, Radhapuram, Vallioor, Keelapavoor, Kadayanallur, Shencottai, Tenkasi and Vasudevanallur. Tahsildars in this district are in charge of the Revenue administration at taluk level. A Tahsildar is assisted by Head Quarters Deputy Tahsildar, Zonal Deputy Tahsildars and Taluk Supply Officer. Each taluk is divided into a number of firkas which comprises a number of Revenue villages. Revenue Inspector at firka level and Village Administrative Officer at Village level assist the Tahsildar.